Attention David Willis!
OH MAN
Mountain Dew and OJ? you mean Mountain Dew Throwback?
Wow Grenade Nipples looks kinda badass!
(Source: rascalthecat, via charactermodel)
persona 3: you walk up stairs at night
Nocturne: you gradually realize you hate everything.
Because someone else did Nocturne, I’ll do a game I played today.
Xenoblade Chronicles: You get destroyed by giant caterpillars
Monkey Island.
You pick up things and use them sometimes.
The Legend of Zelda.
You’re not Zelda.
Okami
You paint everything to death.
Mario Party
All of your friends are assholes
Borderlands. There’s numbers everywhere when you hit enemies.
Sonic the Hedgehog. Run Right.
Dungeons and Dragons
Sitting around a table and talking about the die you just rolled.
Super Mario RPG: Legend of the not being able to jump on things to kill them and taking turns slapping each other instead.
world of nerf your favorite class craft
portal 1/2
everything is a lie and everyone hates you
Pokemon
Every parent is a dead beat who send their 10 year-olds out into the wild to participate in glorified cock fighting. And get attacked by the mafia in that region. And spend their hard earned money on useless shit.
:D
Tron 2.0
While stuck inside this painfully glowy world you have to fight computer viruses face to face with a frisbee
(Source: effyeahpegasister)
A great article by our WONDERFUL friends over at Central Track
I’m the pudgy white arm in pic 5
A University of Copenhagen team has identified the gene which around 6-10,000 years ago underwent a genetic mutation in one individual who eventually gave rise to all blue-eyed people.
Professor Eiberg from the Department of Cellular and Molecular Medicine began his research in 1996, when he “first implicated the OCA2 gene as being responsible for eye colour”, as ScienceDaily puts it.
Over the next decade, he and his colleagues “examined mitochondrial DNA and compared the eye colour of blue-eyed individuals” in countries including Denmark, Jordan and Turkey.Eiberg explained: “Originally, we all had brown eyes. But a genetic mutation affecting the OCA2 gene in our chromosomes resulted in the creation of a ‘switch’, which literally ‘turned off’ the ability to produce brown eyes.”
Specifically, ScienceDaily explains, the OCA2 gene “codes for the so-called P protein, which is involved in the production of melanin”. The “switch”, located in the gene adjacent to OCA2, doesn’t turn off the gene entirely, but “limits its action to reducing the production of melanin in the iris”, thus “diluting” brown eyes to blue.
That the switch doesn’t entirely disable the OCA2 gene is significant, because a complete shut-down of melanin production would result in albinism.
The proof that all blue-eyed people have a common ancestor comes from the fact that whereas eye colours ranging from brown to green are caused by relatively large differences in the amount of melanin in the iris, controlled by “considerable individual variation” in the area of the DNA responsible for melanin production, the variation in iris melanin levels across all blue-eyed individuals is very small.
Eiberg elaborated: “From this we can conclude that all blue-eyed individuals are linked to the same ancestor. They have all inherited the same switch at exactly the same spot in their DNA.”
Eiberg noted that the blue eyes mutation is neither “positive nor negative”, since it doesn’t affect chances of survival. He concluded: “It simply shows that nature is constantly shuffling the human genome, creating a genetic cocktail of human chromosomes and trying out different changes as it does so.”
This is an old article, but I just came across it this morning and thought I’d share.
The human genome is fascinating. :3c
This means I’m related to all of you, so you all better start behaving or I’ll have to start being the stern uncle.
Someone needs to give Ryan Smolkin a Nobel Prize I swear to god
oh GOD
Online personality JewWario went to try poutine at the place these came from:
(Source: badcgijosh)